SCHEMBL18724752

SCHEMBL18724752

CC(C)(C)OC(=O)N[C@H](Cc1ccc(-c2cc(Cl)ccc2F)cc1)CC(O)C=O

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19190257 0.89 MME (0.53) MME
SCHEMBL17011376 0.89 MME (0.53) MME
SCHEMBL16930520 0.85 MME (0.55) MME
SCHEMBL20280997 0.85 MME (0.55) MME
SCHEMBL2875545 0.84 MME (0.62) MME
SCHEMBL15939008 0.84 MME (0.62) MME
SCHEMBL24380938 0.84 MMEL1 (0.43) MME
SCHEMBL16942452 0.83 MME (0.48) MME
SCHEMBL18626444 0.83 MME (0.57) MME
SCHEMBL16941439 0.83 MME (0.67) MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2864292-B1 NEPRILYSIN INHIBITORS THERAVANCE BIOPHARMA R&D IP LLC (US) 2017-04-12 — — EP disclosed
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