Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.46 |
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211307 | 0.92 | PPARD (0.55) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211696 | 0.90 | PPARD (0.44) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL19190806 | 0.89 | PPARD (0.49) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211308 | 0.85 | PPARD (0.37) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL19190832 | 0.81 | PPARD (0.48) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211403 | 0.80 | PPARD (0.58) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL17431416 | 0.80 | PPARA (0.38) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211857 | 0.79 | PPARD (0.48) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211172 | 0.79 | PPARD (0.54) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL17444853 | 0.78 | PPARD (0.47) | PPARDPPARAPPARGITGB3ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-B1 | AROMATIC RING COMPOUND AS GHRELIN O-ACYLTRANSFERASE INHIBITOR | TAKEDA PHARMACEUTICALS CO (JP) | 2017-08-02 | — | — | EP | disclosed |