Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 16/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18940537 | 0.83 | CDC7 (0.45) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL28042900 | 0.74 | CYP19A1 (0.53) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL30768345 | 0.74 | CYP19A1 (0.49) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL1892608 | 0.74 | CYP19A1 (0.49) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL3224575 | 0.74 | CDC7 (0.50) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL18821827 | 0.74 | CYP19A1 (0.49) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL29509135 | 0.74 | MAPT (0.68) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL255050 | 0.74 | MAPT (0.68) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL10197253 | 0.74 | CYP19A1 (0.49) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL6741126 | 0.71 | CYP19A1 (0.74) | CYP19A1MAPTCDC7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| EP-3720851-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AS HISTONE DEACETYLASE 6 INHIBITORS | Oryzon Genomics, S.A. (ES) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019110663-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AS HISTONE DEACETYLASE 6 INHIBITORS | ORYZON GENOMICS, S.A. (ES) | 2019-06-13 | — | — | WO | disclosed |
| EP-2231663-B1 | 6-([1,2,4]TRIAZOLO[4,3-A]PYRIDIN-3-YLMETHYL)-1,6-NAPHTHYRIDIN-5(6H)-ONE DERIVATIVES AS C-MET INHIBITORS | AMGEN INC (US) | 2017-08-02 | — | — | EP | disclosed |