Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 15/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27976818 | 0.87 | CDC7 (0.45) | CYP19A1MAPTCDC7CDK2SLC22A12 | |
| SCHEMBL3224575 | 0.74 | CDC7 (0.50) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL18821827 | 0.74 | CYP19A1 (0.49) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL10197253 | 0.74 | CYP19A1 (0.49) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL29509135 | 0.74 | MAPT (0.68) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL255050 | 0.74 | MAPT (0.68) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL1892608 | 0.74 | CYP19A1 (0.49) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL30768345 | 0.74 | CYP19A1 (0.49) | CYP19A1MAPTCDC7CDK2SLC22A12 | |
| SCHEMBL19190841 | 0.74 | CYP19A1 (0.49) | CYP19A1MAPTCDC7CDK2 | |
| SCHEMBL18822052 | 0.74 | CYP19A1 (0.45) | CYP19A1MAPTCDC7CDK2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105530932-B | Primary formamide as BTK inhibitor | 艾伯维公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-106459042-B | Anti-fibrotic pyridinones | 英特穆恩公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-109069481-A | Methods and compounds for restoring function of mutant p53 | 皮姆维制药公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-105143203-A | N-piperidin-3-ylbenzamide derivatives for the treatment of cardiovascular diseases | PFIZER | 2015-12-09 | — | — | CN | disclosed |