Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 9/20 | 0.64 |
| ▸ | PTGES | O14684 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18629758 | 0.90 | TRPV1 (0.63) | CHEK2HPSETRPV1 | |
| SCHEMBL4182601 | 0.85 | CHEK2 (0.67) | CHEK2PTGESALOX5LTC4SKDM4E | |
| SCHEMBL9058427 | 0.82 | HDAC6 (0.62) | KDM4EALDH1A1HPGDNFKB1SMN1; SMN2 | |
| SCHEMBL19521599 | 0.81 | SMN1; SMN2 (0.52) | KDM4ENPC1ALDH1A1TP53HPGD | |
| SCHEMBL4182129 | 0.81 | NPC1 (0.84) | CHEK2KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL20747785 | 0.79 | CHEK2 (0.65) | CHEK2PTGESALOX5LTC4SKDM4E | |
| SCHEMBL4188962 | 0.78 | MEN1 (0.76) | CHEK2PTGESALOX5LTC4SKDM4E | |
| SCHEMBL4188790 | 0.78 | CHEK2 (0.71) | CHEK2PTGESALOX5LTC4SKDM4E | |
| SCHEMBL26358087 | 0.78 | HDAC6 (0.60) | KDM4ENPC1ALDH1A1HPGDNFKB1 | |
| SCHEMBL4184180 | 0.78 | DGAT1 (0.78) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935125-B1 | ELECTROCHEMICAL WATER TREATMENT SYSTEM AND METHOD | GEN ELECTRIC (US) | 2017-08-02 | — | — | EP | disclosed |