Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 15/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18724747 | 0.82 | FFAR4 (0.39) | FFAR4HCRTR1HCRTR2 | |
| SCHEMBL16939239 | 0.82 | FFAR4 (0.39) | FFAR4HCRTR1HCRTR2 | |
| SCHEMBL19573831 | 0.80 | FFAR1 (0.38) | FFAR4FFAR1 | |
| SCHEMBL14900588 | 0.73 | RORC (0.39) | FFAR4 | |
| SCHEMBL18027484 | 0.72 | FFAR4 (0.39) | FFAR4HCRTR1HCRTR2 | |
| SCHEMBL14919044 | 0.69 | GRM2 (0.42) | — | |
| SCHEMBL14890375 | 0.69 | GRM2 (0.42) | — | |
| SCHEMBL9929765 | 0.69 | CYP3A4 (0.36) | — | |
| SCHEMBL18175828 | 0.69 | CYP3A4 (0.36) | — | |
| SCHEMBL18874807 | 0.68 | NR1H2 (0.41) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3199517-A1 | NEPRILYSIN INHIBITORS | Theravance Biopharma R&D IP, LLC (US) | 2017-08-02 | — | — | EP | disclosed |