Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19191432 | 0.83 | MET (0.61) | MET | |
| SCHEMBL18885868 | 0.83 | MET (0.62) | MET | |
| SCHEMBL18885818 | 0.82 | MET (0.44) | MET | |
| SCHEMBL18885688 | 0.77 | MET (0.45) | MET | |
| SCHEMBL9910493 | 0.77 | MET (1.00) | MET | |
| SCHEMBL10242446 | 0.75 | MET (1.00) | MET | |
| SCHEMBL19190579 | 0.72 | MET (0.48) | MET | |
| SCHEMBL13772558 | 0.71 | MET (0.50) | MET | |
| SCHEMBL19190665 | 0.68 | MET (0.50) | MET | |
| SCHEMBL9910450 | 0.68 | MET (1.00) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231663-B1 | 6-([1,2,4]TRIAZOLO[4,3-A]PYRIDIN-3-YLMETHYL)-1,6-NAPHTHYRIDIN-5(6H)-ONE DERIVATIVES AS C-MET INHIBITORS | AMGEN INC (US) | 2017-08-02 | — | — | EP | disclosed |