Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 5/20 | 0.71 |
| ▸ | MTOR | P42345 | 1/20 | 0.71 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29653627 | 0.83 | PLK1 (1.00) | PLK1MTORVCAM1CYP1A2CYP3A4 | |
| SCHEMBL5171474 | 0.83 | PLK1 (1.00) | PLK1MTORVCAM1CYP1A2CYP3A4 | |
| SCHEMBL5173548 | 0.64 | PLK1 (0.71) | PLK1MTORCYP1A2CYP3A4CYP2D6 | |
| Cyclapolin 9 SCHEMBL31560145 | 0.64 | PLK1 (1.00) | PLK1MTORCYP1A2CYP3A4CYP2D6 | |
| Cyclapolin 9 SCHEMBL5055142 | 0.64 | PLK1 (1.00) | PLK1MTORCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1115892 | 0.64 | VCAM1 (0.51) | PLK1MTORVCAM1CYP1A2CYP3A4 | |
| SCHEMBL17744615 | 0.64 | EGFR (0.60) | VCAM1MAPTALDH1A1MEN1POLB | |
| SCHEMBL7371195 | 0.63 | VCAM1 (0.54) | VCAM1CYP3A4MAPTGRIN2DGRIN3B | |
| SCHEMBL1202036 | 0.63 | VCAM1 (0.46) | PLK1MTORVCAM1MAPTGRIN2D | |
| SCHEMBL12153062 | 0.62 | VCAM1 (0.53) | PLK1MTORVCAM1MAPTGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627322-B1 | METHODS OF TREATING GIARDIASIS | US HEALTH (US) | 2017-08-02 | — | — | EP | disclosed |