Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707615 | 0.80 | NPC1 (0.63) | RXRANR1H2NR1H3NPC1RAB9A | |
| SCHEMBL3676529 | 0.80 | NPC1 (0.63) | RXRANR1H2NR1H3NPC1RAB9A | |
| SCHEMBL19193464 | 0.80 | SLC5A1 (0.54) | RXRANR1H2NR1H3SLC5A1SLC16A3 | |
| SCHEMBL12361456 | 0.75 | RXRA (0.52) | RXRANR1H2NR1H3NPC1RAB9A | |
| SCHEMBL14828287 | 0.73 | SLC5A1 (0.52) | RXRANR1H2NR1H3SLC5A1SLC16A3 | |
| SCHEMBL3471943 | 0.70 | RXRA (0.62) | RXRANR1H2NR1H3SLC5A1SLC16A3 | |
| SCHEMBL3473836 | 0.70 | RXRA (0.68) | RXRANR1H2NR1H3SLC5A1NR3C2 | |
| SCHEMBL21254035 | 0.69 | NPC1 (0.54) | SLC5A1NPC1RAB9A | |
| SCHEMBL3474342 | 0.68 | RXRA (0.65) | RXRANR1H2NR1H3SLC5A1SLC16A3 | |
| SCHEMBL19192750 | 0.68 | NPC1 (0.61) | SLC5A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3199533-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 2017-08-02 | — | — | EP | disclosed |