Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11033875 | 0.79 | CYP4F2 (0.41) | CYP4F2CYP4A11MAPTMMENPSR1 | |
| SCHEMBL2876322 | 0.79 | CYP4F2 (0.41) | CYP4F2CYP4A11MAPTNPSR1 | |
| SCHEMBL20082877 | 0.74 | CYP4F2 (0.42) | CYP4F2CYP4A11MAPTNPSR1 | |
| SCHEMBL9959154 | 0.73 | CYP4F2 (0.44) | CYP4F2CYP4A11 | |
| SCHEMBL15461498 | 0.73 | MAPT (0.43) | MAPTNPSR1 | |
| SCHEMBL1468666 | 0.70 | CYP4F2 (0.36) | CYP4F2CYP4A11MAPTNPSR1 | |
| SCHEMBL1470338 | 0.70 | CYP4F2 (0.36) | CYP4F2CYP4A11MAPTNPSR1 | |
| SCHEMBL12141036 | 0.70 | CYP4F2 (0.39) | CYP4F2CYP4A11MAPTNPSR1 | |
| SCHEMBL1467530 | 0.70 | CYP4F2 (0.36) | CYP4F2CYP4A11MAPTNPSR1 | |
| SCHEMBL2940467 | 0.69 | CYP4F2 (0.57) | CYP4F2CYP4A11MAPTMMENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654422-B1 | Bicyclo[3.2.1]octyl amide derivatives as allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5 or mGluR5) for the treatment of central nervous system (CNS) disorders | H LUNDBECK AS (DK) | 2017-08-02 | — | — | EP | disclosed |