Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13190989 | 0.93 | HTT (0.66) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12267326 | 0.87 | HTT (0.59) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL19677468 | 0.87 | HTT (0.59) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL13998802 | 0.87 | HTT (0.58) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL27378768 | 0.86 | HTT (0.58) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL22043340 | 0.86 | HTT (0.58) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12267322 | 0.86 | AR (0.72) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL21779296 | 0.86 | HTT (0.57) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL22043203 | 0.85 | HTT (0.57) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL26461593 | 0.85 | HTT (0.57) | HTTHIF1AARKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739223-B2 | Surface primer compositions and methods of use | ENVISTA (US) | 2023-08-29 | — | — | US | disclosed |
| US-20230112086-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2023-04-13 | — | — | US | disclosed |
| US-11453790-B2 | Photo-cleavable primer compositions and methods of use | ENVISTA (US) | 2022-09-27 | — | — | US | disclosed |
| US-11352512-B2 | Surface primer compositions and methods of use | ENVISTA (US) | 2022-06-07 | — | — | US | disclosed |
| US-20200347247-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ENVISTA (US) | 2020-11-05 | — | — | US | disclosed |
| US-20200347248-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | ENVISTA (US) | 2020-11-05 | — | — | US | disclosed |
| US-20170217999-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2017-08-03 | — | — | US | disclosed |
| US-20170217997-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217999-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, GRIN1 | HTT 4681/4885HIF1A 311/4885AR 36/4885 |
| US-11453790-B2 | Photo-cleavable primer compositions and methods of use | SP1, GPER1, ESR1 | HTT 4473/4885HIF1A 290/4885AR 62/4885 |
| US-11352512-B2 | Surface primer compositions and methods of use | SP1, GPER1, GRIN1 | HTT 4681/4885HIF1A 311/4885AR 36/4885 |
| US-20200347247-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, GRIN1 | HTT 4681/4885HIF1A 311/4885AR 36/4885 |
| US-20200347248-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, ESR1 | HTT 4473/4885HIF1A 290/4885AR 62/4885 |
| US-20230112086-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, ESR1 | HTT 4473/4885HIF1A 290/4885AR 62/4885 |
| US-11739223-B2 | Surface primer compositions and methods of use | SP1, GPER1, GRIN1 | HTT 4681/4885HIF1A 311/4885AR 36/4885 |
| US-20170217997-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, ESR1 | HTT 4473/4885HIF1A 290/4885AR 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.