Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13190989 | 0.93 | HTT (0.66) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12267326 | 0.87 | HTT (0.59) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL19677468 | 0.87 | HTT (0.59) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL19193322 | 0.86 | HTT (0.58) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL27378768 | 0.86 | HTT (0.58) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12267322 | 0.86 | AR (0.72) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL26461593 | 0.85 | HTT (0.57) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL22043203 | 0.85 | HTT (0.57) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12267192 | 0.84 | AR (0.61) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12267197 | 0.84 | HTT (0.56) | HTTHIF1AARKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172663-A1 | POLYMER-LIPIDS AND COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172663-A1 | POLYMER-LIPIDS AND COMPOSITIONS | PHOSPHO1, PEBP1, PBDC1 | HTT 2763/4885HIF1A 4273/4885AR 2904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.