Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583390 | 0.86 | ALDH1A1 (0.52) | ALDH1A1NPSR1HTTCYP1A2TSHR | |
| SCHEMBL19193411 | 0.84 | ALDH1A1 (0.51) | ALDH1A1NPSR1HTTCYP1A2TSHR | |
| SCHEMBL2066851 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA | |
| SCHEMBL5583367 | 0.73 | ALDH1A1 (0.51) | ALDH1A1NPSR1HTTCYP1A2TSHR | |
| SCHEMBL30800630 | 0.73 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA | |
| SCHEMBL254406 | 0.73 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA | |
| SCHEMBL1665948 | 0.72 | ALDH1A1 (0.53) | ALDH1A1NPSR1HTTCYP1A2TSHR | |
| SCHEMBL10178099 | 0.72 | ALDH1A1 (0.53) | ALDH1A1NPSR1HTTCYP1A2TSHR | |
| SCHEMBL30111358 | 0.72 | ALDH1A1 (0.53) | ALDH1A1NPSR1HTTCYP1A2TSHR | |
| SCHEMBL1665793 | 0.72 | ALDH1A1 (0.53) | ALDH1A1NPSR1HTTCYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217997-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217997-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, ESR1 | ALDH1A1 869/4885NPSR1 1766/4885HTT 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.