Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1918572 | 0.90 | CYP3A4 (0.46) | CYP3A4CYP2C8 | |
| SCHEMBL1919003 | 0.89 | CYP2C8 (0.52) | CYP3A4CYP2C8 | |
| SCHEMBL1919876 | 0.89 | CYP3A4 (0.50) | CYP3A4CYP2C8 | |
| SCHEMBL2369708 | 0.89 | CYP3A4 (0.43) | CYP3A4CYP2C8 | |
| SCHEMBL1920422 | 0.88 | CYP3A4 (0.43) | CYP3A4CYP2C8 | |
| SCHEMBL1918510 | 0.86 | CYP3A4 (0.49) | CYP3A4CYP2C8 | |
| SCHEMBL1918986 | 0.85 | CYP3A4 (0.41) | CYP3A4CYP2C8 | |
| SCHEMBL1919024 | 0.84 | CYP2C8 (0.56) | CYP3A4CYP2C8 | |
| SCHEMBL1918584 | 0.84 | CYP3A4 (0.47) | CYP3A4 | |
| SCHEMBL1918583 | 0.83 | CYP3A4 (0.39) | CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545042-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Bristol-Myers Squibb Company (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011112191-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-09-15 | — | — | WO | disclosed |
| EP-2326633-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Bristol-Myers Squibb Company (US) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010030592-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-03-18 | — | — | WO | disclosed |