Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22623111 | 0.91 | GLA (0.67) | GLAATML3MBTL1MEN1KMT2A | |
| SCHEMBL17576885 | 0.89 | GLA (0.54) | GLAATML3MBTL1MEN1KMT2A | |
| SCHEMBL14980458 | 0.85 | GLA (0.70) | GLAATML3MBTL1MEN1KMT2A | |
| SCHEMBL19574089 | 0.84 | ATM (0.95) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL5131693 | 0.81 | ATM (0.67) | GLAATML3MBTL1MEN1KMT2A | |
| SCHEMBL27487132 | 0.80 | ATM (0.85) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL10722542 | 0.80 | ATM (0.85) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL28366947 | 0.80 | ATM (0.85) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL15685301 | 0.79 | ATM (0.69) | GLAATML3MBTL1MEN1KMT2A | |
| SCHEMBL10304081 | 0.79 | POLB (0.68) | GLAMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017131156-A1 | CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 | 2017-08-03 | — | — | WO | disclosed |