Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12259096 | 0.89 | GLA (0.54) | GLATSHREPHX1EPHX2L3MBTL1 | |
| SCHEMBL19199839 | 0.85 | GLA (0.70) | GLATSHRATMEPHX1EPHX2 | |
| SCHEMBL15934094 | 0.84 | L3MBTL1 (0.68) | GLATSHRATML3MBTL1RAB9A | |
| SCHEMBL22623111 | 0.83 | GLA (0.67) | GLATSHRATMEPHX1EPHX2 | |
| SCHEMBL17558012 | 0.82 | GLA (0.57) | GLATSHRATMEPHX1EPHX2 | |
| SCHEMBL10053018 | 0.82 | RAB9A (0.49) | GLATSHRATML3MBTL1RAB9A | |
| SCHEMBL12282233 | 0.81 | KMT2A (0.52) | GLAATML3MBTL1RAB9ANPC1 | |
| SCHEMBL5605136 | 0.81 | ATM (0.54) | GLATSHRATML3MBTL1NPC1 | |
| SCHEMBL27388324 | 0.80 | ATM (0.48) | GLAATML3MBTL1NPC1KMT2A | |
| SCHEMBL12282009 | 0.80 | KDM4E (0.49) | GLAATML3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074834-A1 | FUNCTIONALLY-MODIFIED OLIGONUCLEOTIDES AND SUBUNITS THEREOF | SAREPTA THERAPEUTICS, INC. (US) | 2013-05-23 | — | — | WO | disclosed |