⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31421474 | 1.00 | — | — | |
| SCHEMBL16660695 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL17080252 | 0.98 | — | — | |
| SCHEMBL23709998 | 0.93 | — | — | |
| SCHEMBL22732651 | 0.93 | — | — | |
| SCHEMBL2208177 | 0.93 | — | — | |
| SCHEMBL28031852 | 0.91 | ALDH1A1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL1632902 | 0.91 | EPHX1 (0.34) | — | |
| SCHEMBL23159130 | 0.91 | HPGD (0.36) | — | |
| SCHEMBL14975473 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824629-B | Method for preparing 3-amino-5- (alpha-aminoethyl) tetrahydrofuran by using N-acetylglucosamine | 南京工业大学 | 2022-12-09 | — | — | CN | claimed |
| CN-114085246-A | Bio-based phosphorus-containing flame retardant and preparation method and application thereof | 福建工程学院 | 2022-02-25 | — | — | CN | claimed |
| CN-105254820-B | A kind of preparation method of Early-strength polycarboxylate superplasticizer of carbon containing oxa- ring and products thereof | 上海台界化工有限公司 | 2018-01-05 | — | — | CN | claimed |
| CN-105254820-A | Preparation method of early-strength type polycarboxylate superplasticizer containing carbon-oxygen heterocyclic ring and product of early-strength type polycarboxylate superplasticizer | SHANGHAI TAIJIE CHEMICAL CO LTD | 2016-01-20 | — | — | CN | claimed |
| EP-0355597-A1 | Substituted dioxolanylethylamines, process for their preparation, their use in pesticides, and intermediates | BAYER AG (DE) | 1990-02-28 | — | — | EP | claimed |
| EP-0278352-A2 | Aminomethyl-tetrahydro-furanes | BAYER AG (DE) | 1988-08-17 | — | — | EP | claimed |
| US-4615725-A | Tetrahydrofuran-2-ylmethylamines and fungicidal and plant growth regulating use | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-07 | — | — | US | claimed |
| US-20250289792-A1 | 3-AMINO-4H-BENZO[E][1,2,4]THIADIAZINE 1,1-DIOXIDE DERIVATIVES AS INHIBITORS OF MRGX2 | SOLENT THERAPEUTICS LLC (US) | 2025-09-18 | — | — | US | disclosed |
| CN-114948963-B | Benzolactam compounds as protein kinase inhibitors | 大冢制药株式会社 | 2025-05-27 | — | — | CN | disclosed |
| CN-114072393-B | 3-Amino-4H-benzo [ E ] [1,2,4] thiadiazine 1, 1-dioxide derivatives as MRGX2 inhibitors | 索伦特治疗有限责任公司 | 2025-05-27 | — | — | CN | disclosed |
| US-12247015-B2 | 3-amino-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide derivatives as inhibitors of MRGX2 | SOLENT THERAPEUTICS, LLC (US) | 2025-03-11 | — | — | US | disclosed |
| US-20240368136-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-11-07 | — | — | US | disclosed |
| EP-3604305-B1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | WAKUNAGA PHARMA CO LTD (JP) | 2024-08-28 | — | — | EP | disclosed |
| US-5175285-A | POLYMERS DERIVED FROM POLYSUCCINIMIDE, USED AS SURFACE COATINGS FOR MEDICINALS AND FOODS | ROHM GMBH CHEMISCHE FABRIK (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0406623-A2 | Polyaspartic acid derivatives as a coating for pharmaceutical forms and foodstuffs | Röhm GmbH (DE) | 1991-01-09 | — | — | EP | disclosed |
| EP-0355597-A1 | Substituted dioxolanylethylamines, process for their preparation, their use in pesticides, and intermediates | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |
| EP-0355597-A1 | Substituted dioxolanylethylamines, process for their preparation, their use in pesticides, and intermediates | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |
| EP-0278352-A2 | Aminomethyl-tetrahydro-furanes | BAYER AG (DE) | 1988-08-17 | — | — | EP | disclosed |
| US-4200752-A | FLUORESCENT DYES | BERTELSON ROBERT C | 1980-04-29 | — | — | US | disclosed |
| US-3990881-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1976-11-09 | — | — | US | disclosed |