SCHEMBL1920044

SCHEMBL1920044

C=CC(Cc1ccccc1)(C(=O)c1ccc(N2CCOCC2)cc1)N(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.46
MAPT P10636 6/20 0.45
MAOB P27338 1/20 0.45
L3MBTL1 Q9Y468 3/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
ALDH1A1 P00352 2/20 0.42
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
ESR1 P03372 1/20 0.41
GSK3B P49841 1/20 0.41
ALOX12 P18054 1/20 0.41
LMNA P02545 1/20 0.41
AOC3 Q16853 2/20 0.40
SLC13A5 Q86YT5 1/20 0.40
RORC P51449 1/20 0.39
PIK3CD O00329 1/20 0.39
PIK3CA P42336 1/20 0.39
PIK3CB P42338 1/20 0.39
PIK3CG P48736 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7069938 0.89 SMN1; SMN2 (0.45) SMN1; SMN2MAPTMAOBL3MBTL1MEN1
SCHEMBL8899177 0.83 SMN1; SMN2 (0.45) SMN1; SMN2MAPTMAOBL3MBTL1MEN1
SCHEMBL8898916 0.83 SMN1; SMN2 (0.51) SMN1; SMN2MAPTMAOBL3MBTL1MEN1
SCHEMBL2774235 0.82 SMN1; SMN2 (0.50) SMN1; SMN2MAPTMAOBL3MBTL1MEN1
Formaldehyde SCHEMBL28335498 0.80 SMN1; SMN2 (0.46) SMN1; SMN2MAPTMAOBL3MBTL1MEN1
SCHEMBL304346 0.80 SMN1; SMN2 (0.48) SMN1; SMN2MAPTMAOBL3MBTL1MEN1
SCHEMBL28990186 0.80 SMN1; SMN2 (0.48) SMN1; SMN2MAPTMAOBL3MBTL1MEN1
SCHEMBL3397043 0.80 SMN1; SMN2 (0.48) SMN1; SMN2MAPTMAOBL3MBTL1MEN1
SCHEMBL35868 0.80 SMN1; SMN2 (0.48) SMN1; SMN2MAPTMAOBL3MBTL1MEN1
SCHEMBL28131034 0.80 SMN1; SMN2 (0.48) SMN1; SMN2MAPTMAOBL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2089334-B1 D1369 D RADIATION CURABLE SECONDARY COATING FOR OPTICAL FIBER DSM IP ASSETS BV (NL) 2011-06-01 EP disclosed
US-6261687-B1 BLEND CONTAINING CHELATED METAL OXIDE RELIANCE ELECTRIC TECHNOLOGIES, LLC 2001-07-17 US disclosed
US-6224979-B1 INSULATING RESIN WITH CORONA RESISTANCE IN ELECTRICAL MOTORS, POLYMERIZATION MATERIAL AND A POLYCONDENSATION PRODUCT OF A PARTIALLY HYDROLYZED CHELATED METAL OXIDE PRECURSOR. RELIANCE ELECTRIC TECHNOLOGIES, LLC 2001-05-01 US disclosed
US-6159600-A Oxygen plasma resistant polymer for electrical devices RELIANCE ELECTRIC TECHNOLOGIES, LLC (US) 2000-12-12 US disclosed
US-5962608-A LIQUID PHASE; HYDROLYSIS OF AN ORGANOMETALLIC COMPOUND RELIANCE ELECTRIC INDUSTRIAL CO. (US) 1999-10-05 US disclosed
US-5948514-A Photocurable thermosettting resin composition developable with aqueous alkali solution TAIYO INK MANUFACTURING CO., LTD. (JP) 1999-09-07 US disclosed
US-5780525-A Photocurable composition for electrical insulation RELIANCE ELECTRIC INDUSTRIAL COMPANY (US) 1998-07-14 US disclosed