Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19200959 | 0.89 | KCNH2 (0.43) | KCNH2CTSKKDM4D | |
| SCHEMBL17494486 | 0.89 | KCNH2 (0.47) | KCNH2BTK | |
| SCHEMBL19194853 | 0.87 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL19194759 | 0.86 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL19200526 | 0.86 | CTSK (0.43) | SUV39H2CTSKKDM4DDPP4JAK3 | |
| SCHEMBL19200393 | 0.85 | KCNH2 (0.60) | KCNH2SUV39H2CTSKKDM4DDPP4 | |
| SCHEMBL17494367 | 0.83 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL17494369 | 0.83 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL19194825 | 0.82 | KCNH2 (0.41) | KCNH2KDM4D | |
| SCHEMBL19200960 | 0.82 | CTSK (0.39) | SUV39H2CTSKKDM4DDPP4JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217897-A1 | QUINOLONE DERIVATIVES AS ANTIBACTERIALS | WUXI APPTEC (CN) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217897-A1 | QUINOLONE DERIVATIVES AS ANTIBACTERIALS | TOP1, NQO2, TOP2A | KCNH2 3467/4885SUV39H2 3421/4885CTSK 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.