Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 2/20 | 0.39 |
| ▸ | OXTR | P30559 | 8/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19182798 | 1.00 | GRM7 (0.39) | GRM7OXTRCYP3A4AVPR2AVPR1A | |
| SCHEMBL19200400 | 0.89 | GRM7 (0.41) | GRM7OXTRCYP3A4AVPR2AVPR1A | |
| SCHEMBL19200271 | 0.89 | GRM7 (0.41) | GRM7OXTRCYP3A4AVPR2AVPR1A | |
| SCHEMBL19183412 | 0.89 | GRM7 (0.41) | GRM7OXTRCYP3A4AVPR2AVPR1A | |
| SCHEMBL19200313 | 0.87 | OXTR (0.40) | GRM7OXTRCYP3A4AVPR2AVPR1A | |
| SCHEMBL19182901 | 0.86 | GRM7 (0.40) | GRM7OXTRCYP3A4AVPR2AVPR1A | |
| SCHEMBL19200515 | 0.86 | GRM7 (0.40) | GRM7OXTRCYP3A4AVPR2AVPR1A | |
| Formic Acid SCHEMBL20678734 | 0.86 | GRM7 (0.38) | GRM7OXTRCYP3A4AVPR2AVPR1A | |
| SCHEMBL19183402 | 0.85 | GRM7 (0.36) | GRM7OXTRCYP3A4AVPR2AVPR1A | |
| SCHEMBL19183501 | 0.85 | GRM7 (0.52) | GRM7OXTRCYP3A4AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017131221-A1 | INDANE DERIVATIVES AS MGLUR7 MODULATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-08-03 | — | — | WO | disclosed |