Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 5/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17431198 | 0.80 | ESR2 (0.40) | ESR2ESR1ALOX5PGRPRKDC | |
| SCHEMBL17689908 | 0.79 | ESR2 (0.49) | ESR2ESR1ALOX5MEN1KMT2A | |
| SCHEMBL19419237 | 0.79 | ESR2 (0.46) | ESR2ESR1ALOX5MEN1KMT2A | |
| SCHEMBL18566661 | 0.75 | ESR2 (0.42) | ESR2ESR1ALOX5PGRPRKDC | |
| SCHEMBL19803007 | 0.74 | PRKDC (0.50) | ESR2ESR1ALOX5PRKDCGPR3 | |
| SCHEMBL18566660 | 0.73 | PARP14 (0.42) | ESR2ESR1ALOX5PRKDCPARP14 | |
| SCHEMBL9890859 | 0.73 | ALOX5 (0.43) | ESR2ESR1ALOX5PRKDCGPR3 | |
| SCHEMBL20247042 | 0.73 | ALOX5 (0.38) | ESR2ALOX5MEN1CYP2C19KMT2A | |
| SCHEMBL17039877 | 0.72 | PRKDC (0.49) | ESR2ESR1ALOX5PRKDCGPR3 | |
| SCHEMBL21583609 | 0.72 | PRKDC (0.49) | ESR2ESR1ALOX5PRKDCGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170222155-A1 | CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING | SFC CO., LTD. (KR) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170222155-A1 | CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING | CCNE2, INF2, AFF4 | ESR2 842/4885ESR1 230/4885ALOX5 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.