Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803215 | 0.77 | CYP1A2 (0.53) | RAB9ANPC1PDE10AALDH1A1HPGD | |
| SCHEMBL4548619 | 0.77 | NR1I2 (0.37) | RAB9ANPC1ALDH1A1HPGDALOX15 | |
| SCHEMBL21920584 | 0.77 | CYP1A2 (0.53) | RAB9ANPC1ALDH1A1HPGDALOX15 | |
| SCHEMBL10272520 | 0.75 | CYP2A6 (0.42) | RAB9ANPC1PDE10ALMNA | |
| SCHEMBL21451242 | 0.75 | CCR9 (0.43) | RAB9AALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL25449345 | 0.75 | PDPK1 (0.52) | RAB9ANPC1ALDH1A1HPGDALOX15 | |
| SCHEMBL10272932 | 0.75 | CYP2A6 (0.42) | PDE10AALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL23033200 | 0.74 | PDE10A (0.34) | PDE10AALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL30010382 | 0.74 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1HPGDALOX15 | |
| SCHEMBL348347 | 0.74 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132173-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMACEUTICALS, INC. (US) | 2017-08-03 | — | — | WO | disclosed |