Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19203949 | 0.93 | WNK1 (0.50) | WNK1MEN1KMT2AALDH3A1LMNA | |
| SCHEMBL19204111 | 0.91 | WNK1 (0.48) | WNK1MEN1KMT2AALDH3A1LMNA | |
| SCHEMBL1699924 | 0.89 | WNK1 (0.51) | WNK1MEN1KMT2AALDH3A1LMNA | |
| SCHEMBL1700167 | 0.83 | WNK1 (0.47) | WNK1KMT2ALMNAL3MBTL1MAPT | |
| SCHEMBL1700375 | 0.83 | WNK1 (0.47) | WNK1KMT2ALMNAL3MBTL1MAPT | |
| SCHEMBL1700178 | 0.83 | WNK1 (0.47) | WNK1KMT2ALMNAL3MBTL1MAPT | |
| SCHEMBL2480893 | 0.82 | WNK1 (0.52) | WNK1MEN1KMT2AALDH3A1LMNA | |
| SCHEMBL1699907 | 0.82 | WNK1 (0.50) | WNK1MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL30921518 | 0.82 | WNK1 (0.50) | WNK1MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL1699910 | 0.82 | WNK1 (0.50) | WNK1MEN1KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132474-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2017-08-03 | — | — | WO | disclosed |