Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.63 |
| ▸ | CTNNB1 | P35222 | 7/20 | 0.54 |
| ▸ | WNT3A | P56704 | 7/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990191 | 0.91 | PRKCI (0.69) | PRKCICTNNB1WNT3ADYRK1ADYRK1B | |
| SCHEMBL29654041 | 0.83 | PRKCI (0.63) | PRKCICTNNB1WNT3ADYRK1ACLK1 | |
| SCHEMBL8319676 | 0.83 | PRKCI (0.63) | PRKCICTNNB1WNT3ADYRK1ACLK1 | |
| SCHEMBL12348374 | 0.79 | PRKCI (0.47) | PRKCIPLAU | |
| SCHEMBL16742246 | 0.79 | PRKCI (0.61) | PRKCICTNNB1WNT3ATSHRTAS1R3 | |
| SCHEMBL31262479 | 0.78 | CTNNB1 (0.67) | PRKCICTNNB1WNT3ADYRK1ACLK1 | |
| SCHEMBL875455 | 0.78 | CTNNB1 (0.67) | PRKCICTNNB1WNT3ADYRK1ACLK1 | |
| SCHEMBL3544882 | 0.77 | PRKCI (1.00) | PRKCICTNNB1WNT3ADYRK1ATSHR | |
| SCHEMBL20572734 | 0.77 | TSHR (0.67) | CTNNB1TSHRNPC1RAB9APLAU | |
| SCHEMBL1726294 | 0.77 | CTNNB1 (0.61) | PRKCICTNNB1WNT3ADYRK1ACLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017131425-A1 | NOVEL IMIDAZOLE DERIVATIVE HAVING JNK INHIBITORY ACTIVITY AND USE THEREOF | 한양대학교 에리카산학협력단 | 2017-08-03 | — | — | WO | disclosed |