Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.69 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204501 | 0.91 | PRKCI (0.63) | PRKCITAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL12348374 | 0.83 | PRKCI (0.47) | PRKCIPRSS1PRSS2PRSS3 | |
| SCHEMBL2176489 | 0.81 | PRKCI (0.69) | PRKCITAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL29503137 | 0.81 | PRKCI (0.69) | PRKCITAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL3544882 | 0.81 | PRKCI (1.00) | PRKCITAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL20572734 | 0.81 | TSHR (0.67) | RAB9ANPC1TSHRCTNNB1MAPT | |
| SCHEMBL6328340 | 0.81 | PRKCI (0.58) | PRKCITAS1R3TAS1R1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL28130087 | 0.80 | PRKCI (0.67) | PRKCITAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL11022359 | 0.79 | PRKCI (0.66) | PRKCITAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL6328342 | 0.79 | PRKCI (0.65) | PRKCITAS1R3TAS1R1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020022787-A1 | NOVEL IMIDAZOLE DERIVATIVE HAVING JNK INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 삼진제약주식회사 | 2020-01-30 | — | — | WO | disclosed |
| US-6288230-B1 | COMPOUNDS FOR TREATMENT OF PSYCHOLOGICAL DISORDERS | NEUROGEN CORPORATION | 2001-09-11 | — | — | US | disclosed |