Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 13/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1196822 | 1.00 | F11 (0.44) | F11KLKB1SNCACACNA1GCACNA1H | |
| SCHEMBL1196922 | 0.85 | F11 (0.47) | F11KLKB1 | |
| SCHEMBL1196960 | 0.78 | F11 (0.47) | F11KLKB1 | |
| SCHEMBL1197057 | 0.78 | F11 (0.63) | F11KLKB1 | |
| SCHEMBL1197333 | 0.78 | F11 (0.63) | F11KLKB1 | |
| SCHEMBL1196804 | 0.76 | F11 (0.74) | F11KLKB1 | |
| SCHEMBL1197275 | 0.76 | F11 (0.74) | F11KLKB1 | |
| SCHEMBL8241654 | 0.76 | F11 (0.51) | F11KLKB1 | |
| SCHEMBL1196478 | 0.75 | F11 (0.52) | F11KLKB1 | |
| SCHEMBL1196737 | 0.74 | F11 (0.49) | F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981854-B1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-06-01 | — | — | EP | disclosed |