Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19995332 | 0.87 | PIK3CD (0.36) | — | |
| SCHEMBL4813209 | 0.76 | CA14 (0.40) | SMN1; SMN2CA14THRBTSHR | |
| SCHEMBL19492 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2CA14TSHRHSD17B10 | |
| SCHEMBL26980517 | 0.75 | POLB (0.34) | SMN1; SMN2 | |
| SCHEMBL14800004 | 0.74 | SMN1; SMN2 (0.34) | SMN1; SMN2CA14THRBTSHRTP53 | |
| SCHEMBL12875937 | 0.74 | SMN1; SMN2 (0.34) | SMN1; SMN2CA14THRBTSHRTP53 | |
| SCHEMBL1378958 | 0.74 | SMN1; SMN2 (0.34) | SMN1; SMN2CA14THRBTSHRTP53 | |
| SCHEMBL1417574 | 0.74 | SMN1; SMN2 (0.34) | SMN1; SMN2CA14THRBTSHRTP53 | |
| SCHEMBL6710646 | 0.72 | SMN1; SMN2 (0.33) | SMN1; SMN2CA14THRBTSHR | |
| Hydrochloric Acid SCHEMBL1198489 | 0.72 | SMN1; SMN2 (0.33) | SMN1; SMN2CA14THRBTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017133667-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |