Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14631555 | 0.71 | HSD17B10 (0.44) | ALDH1A1 | |
| SCHEMBL5951848 | 0.67 | MAP2K4 (0.41) | MEN1ALDH1A1KMT2ACYP19A1CYP2C9 | |
| SCHEMBL31190710 | 0.67 | MAP2K4 (0.41) | MEN1ALDH1A1KMT2ACYP19A1CYP2C9 | |
| SCHEMBL15568853 | 0.66 | CYP4F2 (0.39) | ALDH1A1 | |
| SCHEMBL31484933 | 0.66 | CYP4F2 (0.39) | ALDH1A1 | |
| SCHEMBL19831359 | 0.61 | — | — | |
| SCHEMBL25058989 | 0.61 | DAO (0.34) | MEN1ALDH1A1KMT2APARP1 | |
| SCHEMBL7850281 | 0.60 | MEN1 (0.46) | MEN1ALDH1A1KMT2A | |
| SCHEMBL14802047 | 0.60 | GRM2 (0.51) | MEN1ALDH1A1KMT2ACYP11B2 | |
| SCHEMBL20813785 | 0.59 | PARP1 (0.44) | MEN1KMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609883-A1 | FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018188590-A1 | FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-10-18 | — | — | WO | disclosed |
| WO-2017133667-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017133664-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT， AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |