Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL590272 | 0.79 | KDR (0.43) | MEN1ALDH1A1KMT2AKDRFLT3 | |
| SCHEMBL13106209 | 0.79 | ALDH1A1 (0.44) | MEN1ALDH1A1KMT2AKDRFLT3 | |
| SCHEMBL423714 | 0.78 | PDPK1 (0.41) | MEN1ALDH1A1KMT2AKDRFLT3 | |
| SCHEMBL16252856 | 0.76 | SSTR4 (0.49) | MEN1ALDH1A1KMT2AKDRFLT3 | |
| SCHEMBL15995815 | 0.75 | KCNA5 (0.51) | MEN1ALDH1A1KMT2AKDRFLT3 | |
| SCHEMBL6925654 | 0.75 | MAPK13 (0.41) | KDRFLT3LCKCSF1RKIT | |
| SCHEMBL21324100 | 0.75 | ALDH1A1 (0.50) | MEN1ALDH1A1KMT2AKDRFLT3 | |
| SCHEMBL8541078 | 0.75 | ALDH1A1 (0.44) | MEN1ALDH1A1KMT2AKDRFLT3 | |
| SCHEMBL31424340 | 0.74 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2AKDRFLT3 | |
| SCHEMBL16252841 | 0.74 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2AMAPK13EIF2AK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447905-A | Postemergence herbicides | DOWELANCO (US) | 1995-09-05 | — | — | US | claimed |
| CN-113121528-B | Multi-target inhibition compound, composition, functional molecule and application thereof | 中国科学院上海药物研究所 | 2022-12-13 | — | — | CN | disclosed |
| EP-3954679-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HIV INFECTIONS | Gilead Sciences, Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| EP-3409667-B1 | AMIDE COMPOUNDS FOR THE TREATMENT OF HIV INFECTIONS | GILEAD SCIENCES INC (US) | 2021-07-21 | — | — | EP | disclosed |
| CN-113121528-A | Multi-target inhibition compound, composition, functional molecule and application thereof | 中国科学院上海药物研究所 | 2021-07-16 | — | — | CN | disclosed |
| US-20210009555-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2021-01-14 | — | — | US | disclosed |
| US-20210009555-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2021-01-14 | — | — | US | disclosed |
| EP-3110818-B1 | 9H-PYRIMIDO[4,5-B]INDOLES AND RELATED ANALOGS AS BET BROMODOMAIN INHIBITORS | UNIV MICHIGAN REGENTS (US) | 2019-10-23 | — | — | EP | disclosed |
| US-10336727-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2019-07-02 | — | — | US | disclosed |
| US-10253044-B2 | 9H-pyrimido [4,5-b]indoles and related analogs as BET bromodomain inhibitors | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-04-09 | — | — | US | disclosed |
| US-5602075-A | N-aryl[1,2,4]triazolo[1,5-a]pyrazine-2-sulfonamide herbicides | DOWELANCO (US) | 1997-02-11 | — | — | US | disclosed |
| US-5571775-A | EFFECTIVE ON A BROAD SPECTRUM OF VEGETATION AT LOW APPLICATION RATES | DOWELANCO (US) | 1996-11-05 | — | — | US | disclosed |
| US-5534481-A | Indazolesulfonylurea derivative, its use and intermediate for its production | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0717743-A1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5494887-A | Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1996-02-27 | — | — | US | disclosed |
| WO-1996001826-A1 | N-ARYL[1,2,4]TRIAZOLO[1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-01-25 | — | — | WO | disclosed |
| CN-1110478-A | Indazolesulfonylurea derivative, use thereof, and intermediate for production thereof | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1995-10-18 | — | — | CN | disclosed |
| US-5447905-A | Postemergence herbicides | DOWELANCO (US) | 1995-09-05 | — | — | US | disclosed |
| US-5447905-A | Postemergence herbicides | DOWELANCO (US) | 1995-09-05 | — | — | US | disclosed |
| EP-0657450-A1 | INDAZOLESULFONYLUREA DERIVATIVE, USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF | KumaiI Chemical Industry Co., Ltd. (JP) | 1995-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009555-A1 | THERAPEUTIC COMPOUNDS | HAVCR2, SARS1, RPL35 | MEN1 2845/4885ALDH1A1 351/4885KMT2A 4689/4885 |
| US-10253044-B2 | 9H-pyrimido [4,5-b]indoles and related analogs as BET bromodomain inhibitors | BRD4, BRD3, BRD1 | MEN1 1743/4885ALDH1A1 981/4885KMT2A 225/4885 |
| US-10336727-B2 | Histone demethylase inhibitors | KDM1B, KDM5A, KDM5C | MEN1 2685/4885ALDH1A1 306/4885KMT2A 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.