Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204862 | 0.89 | CYP4F2 (0.32) | CYP4F2CYP4A11 | |
| SCHEMBL19204872 | 0.77 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL19204852 | 0.77 | ESR1 (0.35) | ALDH1A1 | |
| SCHEMBL2590096 | 0.73 | GAA (0.37) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL19250505 | 0.70 | CYP4F2 (0.41) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL25210691 | 0.70 | GAA (0.32) | CYP4F2CYP4A11 | |
| SCHEMBL2592535 | 0.70 | ATR (0.35) | CYP4F2CYP4A11 | |
| SCHEMBL29049988 | 0.69 | CYP4F2 (0.36) | CYP4F2CYP4A11 | |
| SCHEMBL19204859 | 0.69 | CYP4F2 (0.47) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL24012792 | 0.69 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |