Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | LITAF | Q99732 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204862 | 0.80 | CYP4F2 (0.32) | RET | |
| SCHEMBL19204857 | 0.77 | CYP4F2 (0.35) | ALDH1A1 | |
| SCHEMBL29005562 | 0.76 | ESR1 (0.42) | ESR1TNFPDE4BPDE4DLITAF | |
| SCHEMBL19204851 | 0.76 | ESR1 (0.42) | ESR1TNFPDE4BPDE4DLITAF | |
| SCHEMBL29005493 | 0.72 | ESR1 (0.40) | ESR1HPGDALDH1A1 | |
| SCHEMBL18448466 | 0.71 | CYP4F2 (0.41) | ALDH1A1 | |
| SCHEMBL25028564 | 0.71 | ESR1 (0.36) | ESR1TNFPDE4BPDE4DLITAF | |
| SCHEMBL2593255 | 0.69 | CNR1 (0.35) | CNR2 | |
| SCHEMBL2590096 | 0.69 | GAA (0.37) | ALDH1A1RET | |
| SCHEMBL31469242 | 0.69 | DRD2 (0.32) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |