Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399385 | 0.94 | CA12 (0.43) | CA12CA9CA2PLA2G2CMCHR1 | |
| SCHEMBL10398217 | 0.92 | PLA2G2C (0.42) | CA12CA9CA2PLA2G2CMCHR1 | |
| SCHEMBL14959201 | 0.91 | CA12 (0.49) | CA12CA9CA2SMN1; SMN2CA1 | |
| SCHEMBL18590289 | 0.91 | CA12 (0.49) | CA12CA9CA2SMN1; SMN2CA1 | |
| SCHEMBL17233364 | 0.91 | CA9 (0.43) | CA12CA9CA2CA1ALDH1A1 | |
| SCHEMBL3581029 | 0.88 | CA12 (0.38) | CA12CA9CA2CA1ALDH1A1 | |
| SCHEMBL8984218 | 0.88 | CA12 (0.47) | CA12CA9CA2PLA2G2CMCHR1 | |
| SCHEMBL10759972 | 0.88 | CA12 (0.38) | CA12CA9CA2CA1ALDH1A1 | |
| SCHEMBL10725680 | 0.88 | CA12 (0.38) | CA12CA9CA2CA1ALDH1A1 | |
| SCHEMBL11363251 | 0.88 | CA12 (0.38) | CA12CA9CA2CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133667-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |