Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18590289 | 1.00 | CA12 (0.49) | CA12CA9CA2CA1STAT3 | |
| SCHEMBL17233364 | 0.94 | CA9 (0.43) | CA12CA9CA2CA1STAT3 | |
| SCHEMBL19204919 | 0.91 | CA12 (0.43) | CA12CA9CA2CA1STAT3 | |
| SCHEMBL8984218 | 0.91 | CA12 (0.47) | CA12CA9CA2CA1STAT3 | |
| SCHEMBL9486162 | 0.89 | CA12 (0.43) | CA12CA9CA2CA1STAT3 | |
| SCHEMBL4574543 | 0.89 | CA12 (0.43) | CA12CA9CA2CA1STAT3 | |
| SCHEMBL8984191 | 0.88 | CA12 (0.44) | CA12CA9CA2CA1STAT3 | |
| SCHEMBL3912342 | 0.86 | CA9 (0.40) | CA12CA9CA2CA1STAT3 | |
| SCHEMBL4203522 | 0.86 | CA2 (0.50) | CA12CA9CA2CA1STAT3 | |
| SCHEMBL4203518 | 0.86 | CA2 (0.50) | CA12CA9CA2CA1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2594561-A1 | Structural variants of mycolactones for use in modulating inflammation, immunity and pain | INSTITUT PASTEUR (FR) | 2013-05-22 | — | — | EP | disclosed |