Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 5/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 12/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004755 | 0.79 | CYP4F2 (0.53) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL18438313 | 0.79 | CYP4F2 (0.50) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL12693554 | 0.79 | CYP4F2 (0.47) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL18133767 | 0.79 | CYP4F2 (0.47) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL18758225 | 0.79 | CYP4F2 (0.47) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL24173879 | 0.79 | ALDH1A1 (0.49) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL19204929 | 0.79 | CYP4F2 (0.47) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL21437982 | 0.78 | CYP4F2 (0.49) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL24947689 | 0.78 | CYP4F2 (0.46) | CYP4F2CYP4A11LMNAALDH1A1POLB | |
| SCHEMBL12497507 | 0.77 | CYP4F2 (0.45) | CYP4F2CYP4A11LMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133667-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |