Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.83 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.67 |
| ▸ | AR | P10275 | 4/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.67 |
| ▸ | HTR6 | P50406 | 1/20 | 0.67 |
| ▸ | ESRRG | P62508 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1862016 | 1.00 | ESR1 (0.83) | ESR1ESR2ARCYP3A4HPGD | |
| Bisphenol A SCHEMBL16581553 | 1.00 | ESR1 (0.83) | ESR1ESR2ARCYP3A4HPGD | |
| SCHEMBL29473780 | 1.00 | ESR1 (0.83) | ESR1ESR2ARCYP3A4HPGD | |
| SCHEMBL20925245 | 0.96 | ESR1 (0.77) | ESR1ESR2ARCYP3A4HPGD | |
| SCHEMBL29696084 | 0.94 | ESR1 (0.95) | ESR1ESR2ARCYP3A4HPGD | |
| SCHEMBL298974 | 0.94 | ESR1 (0.95) | ESR1ESR2ARCYP3A4HPGD | |
| SCHEMBL6523088 | 0.93 | ESR1 (0.71) | ESR1ESR2ARCYP3A4HPGD | |
| SCHEMBL10935934 | 0.93 | ESR1 (0.71) | ESR1ESR2ARCYP3A4HPGD | |
| SCHEMBL22271942 | 0.93 | ESR1 (0.71) | ESR1ESR2ARCYP3A4HPGD | |
| SCHEMBL1416326 | 0.93 | ESR1 (0.71) | ESR1ESR2ARCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732220-B2 | Polymers and polymer blends with enhanced gloss level | COVESTRO LLC (US) | 2017-08-15 | — | — | US | disclosed |