SCHEMBL19205212

SCHEMBL19205212

C=CC=CC(C=Cc1ccccc1)=CC(=C)C=C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.39
HDAC4 P56524 3/20 0.39
HDAC1 Q13547 3/20 0.39
HDAC2 Q92769 3/20 0.39
HDAC8 Q9BY41 3/20 0.39
HDAC6 Q9UBN7 3/20 0.39
PLIN1 O60240 2/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 2/20 0.39
RECQL P46063 2/20 0.39
PLIN5 Q00G26 2/20 0.39
ABHD5 Q8WTS1 2/20 0.39
HDAC7 Q8WUI4 2/20 0.39
HDAC10 Q969S8 2/20 0.39
HDAC11 Q96DB2 2/20 0.39
HDAC9 Q9UKV0 2/20 0.39
HDAC5 Q9UQL6 2/20 0.39
ALDH1A1 P00352 2/20 0.39
TNKS O95271 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7112932 0.92 MAPT (0.45) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL1579931 0.82 HDAC3 (0.53) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL27118327 0.80 GLA (0.46) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL9422101 0.80 ALDH1A1 (0.44) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL954016 0.80 ALDH1A1 (0.44) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL26079487 0.80 ALDH1A1 (0.44) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL1245521 0.80 ALDH1A1 (0.44) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL24093 0.80 ALDH1A1 (0.44) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL17156438 0.79 ALDH1A1 (0.47) HDAC3HDAC4HDAC1HDAC2HDAC8
Water SCHEMBL6447465 0.78 MAPT (0.42) HDAC3HDAC4HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190330403-A1 BLOCK COPOLYMERS INCLUDING HIGH VINYL SEGMENTS LION ELASTOMERS ORANGE, LLC 2019-10-31 US disclosed
US-10400056-B2 Block copolymers including high vinyl segments FIRESTONE POLYMERS, LLC (US) 2019-09-03 US disclosed
US-20180291135-A1 BLOCK COPOLYMERS INCLUDING HIGH VINYL SEGMENTS LION ELASTOMERS ORANGE, LLC 2018-10-11 US disclosed
US-10005874-B2 Block copolymers including high vinyl segments BRIDGESTONE CORPORATION (JP) 2018-06-26 US disclosed
US-20170342187-A1 BLOCK COPOLYMERS INCLUDING HIGH VINYL SEGMENTS LION ELASTOMERS ORANGE, LLC 2017-11-30 US disclosed
US-20170335045-A1 BLOCK COPOLYMERS INCLUDING HIGH VINYL SEGMENTS LION ELASTOMERS ORANGE, LLC 2017-11-23 US disclosed
US-9732178-B1 Block copolymers including high vinyl segments BRIDGESTONE CORPORATION (JP) 2017-08-15 US disclosed