SCHEMBL19205828

SCHEMBL19205828

c1ccc2c(c1)Oc1ccccc1Sc1ccccc1O2

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.41
MAOA P21397 4/20 0.40
MAOB P27338 2/20 0.40
ALOX5 P09917 1/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
BCHE P06276 1/20 0.40
POLB P06746 1/20 0.40
CYP3A4 P08684 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
CNR1 P21554 1/20 0.40
ACHE P22303 1/20 0.40
PTGS1 P23219 1/20 0.40
SLC6A2 P23975 1/20 0.40
HTR2C P28335 1/20 0.40
PTGS2 P35354 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenoxathiine SCHEMBL29396568 0.97 MAOA (0.42) AHRMAOAMAOBALOX5MEN1
Phenoxathiine SCHEMBL29373698 0.97 MAOA (0.42) AHRMAOAMAOBALOX5MEN1
Phenoxathiine SCHEMBL7922 0.97 MAOA (0.42) AHRMAOAMAOBALOX5MEN1
Phenoxathiine SCHEMBL5970725 0.94 MAOA (0.40) AHRMAOAMAOBALOX5MEN1
Phenoxathiine SCHEMBL5699627 0.94 MAOA (0.40) AHRMAOAMAOBALOX5MEN1
Phenoxathiine SCHEMBL10512948 0.94 MAOA (0.40) AHRMAOAMAOBALOX5MEN1
Phenoxathiine SCHEMBL11361313 0.92 MAOA (0.39) AHRMAOAMAOBALOX5MEN1
Phenoxathiine SCHEMBL11361322 0.92 MAOA (0.39) AHRMAOAMAOBALOX5MEN1
SCHEMBL29211168 0.92 AHR (0.42) AHRMAOAMAOBALOX5MEN1
Phenoxathiine SCHEMBL11361319 0.90 MAOA (0.37) AHRMAOAMAOBALOX5MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10596727-B2 Process for manufacturing a densified polymer powder, and process of melt processing a densified polymer powder SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-03-24 US disclosed
EP-3215334-B1 PROCESS FOR MANUFACTURING A DENSIFIED POLYMER POWDER COMPRISING AN INTERFACIAL POLYCARBONATE SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-07-03 EP disclosed
EP-3215334-A2 PROCESS FOR MANUFACTURING A DENSIFIED POLYMER POWDER, AND PROCESS OF MELT PROCESSING A DENSIFIED POLYMER POWDER SABIC Global Technologies B.V. (NL) 2017-09-13 EP disclosed
US-20170232640-A1 PROCESS FOR MANUFACTURING A DENSIFIED POLYMER POWDER, AND PROCESS OF MELT POLYMERIZING A DENSIFIED POLYMER POWDER SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-17 US disclosed