⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451664 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL10927676 | 0.67 | — | — | |
| SCHEMBL1493029 | 0.65 | — | — | |
| SCHEMBL10612935 | 0.65 | — | — | |
| SCHEMBL10667864 | 0.63 | TSHR (0.30) | — | |
| SCHEMBL11212291 | 0.62 | — | — | |
| SCHEMBL4971423 | 0.59 | TSHR (0.32) | — | |
| SCHEMBL8072914 | 0.59 | TSHR (0.32) | — | |
| SCHEMBL575408 | 0.59 | TSHR (0.32) | — | |
| SCHEMBL2920738 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180373-B1 | BIOMATERIAL WITH REDUCED INFLAMMATORY RESPONSE | GOVERNING COUNCIL UNIV TORONTO (CA) | 2021-04-07 | — | — | EP | claimed |
| EP-4702059-A1 | N-CADHERIN TARGETING CHIMERIC PEPTIDES FOR INHIBITING RESTENOSIS | The Governing Council of the University of Toronto (CA) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024221109-A1 | N-CADHERIN TARGETING CHIMERIC PEPTIDES FOR INHIBITING RESTENOSIS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2024-10-31 | — | — | WO | disclosed |
| US-10973950-B2 | Biomaterial with reduced inflammatory response | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2021-04-13 | — | — | US | disclosed |
| EP-3180373-B1 | BIOMATERIAL WITH REDUCED INFLAMMATORY RESPONSE | GOVERNING COUNCIL UNIV TORONTO (CA) | 2021-04-07 | — | — | EP | disclosed |
| US-20170232142-A1 | Biomaterial with Reduced Inflammatory Response | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2017-08-17 | — | — | US | disclosed |