Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459351 | 0.93 | LIPG (0.55) | LIPGTLR8NR1H2NR1H3ALOX5 | |
| SCHEMBL9579594 | 0.91 | LIPG (0.58) | LIPGCYP3A4TYRNR1H2NR1H3 | |
| SCHEMBL17027770 | 0.91 | LIPG (0.58) | LIPGCYP3A4TYRNR1H2NR1H3 | |
| SCHEMBL11354772 | 0.91 | LIPG (0.58) | LIPGCYP3A4TYRNR1H2NR1H3 | |
| SCHEMBL17027739 | 0.91 | LIPG (0.58) | LIPGCYP3A4TYRNR1H2NR1H3 | |
| SCHEMBL17027755 | 0.91 | LIPG (0.58) | LIPGCYP3A4TYRNR1H2NR1H3 | |
| SCHEMBL17027766 | 0.91 | LIPG (0.58) | LIPGCYP3A4TYRNR1H2NR1H3 | |
| SCHEMBL29520482 | 0.88 | LIPG (0.56) | LIPGCYP3A4CYP2D6CYP2C9TLR8 | |
| SCHEMBL245188 | 0.88 | LIPG (0.56) | LIPGCYP3A4CYP2D6CYP2C9TLR8 | |
| SCHEMBL8072359 | 0.86 | LIPG (0.47) | LIPGCYP3A4CYP2D6CYP2C9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3105205-A1 | PYRAZOLONE COMPOUNDS AND USES THEREOF | Inception 2, Inc. (US) | 2016-12-21 | — | — | EP | disclosed |
| EP-3022234-A1 | SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| EP-2935228-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | Inception 2, Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| WO-2015123133-A1 | PYRAZOLONE COMPOUNDS AND USES THEREOF | INCEPTION 2, INC. (US) | 2015-08-20 | — | — | WO | disclosed |
| WO-2015009479-A1 | SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-01-22 | — | — | WO | disclosed |
| WO-2014099503-A1 | TRIAZOLONE COMPOUNDS AND USES THEREOF | INCEPTION 2, INC. (US) | 2014-06-26 | — | — | WO | disclosed |
| CN-101712828-B | Ink jet ink, ink jet recording method, and ink cartridge | CANON KK | 2012-08-22 | — | — | CN | disclosed |
| EP-2326651-A1 | BUPRENORPHINE ANALOGS | Purdue Pharma LP (US) | 2011-06-01 | — | — | EP | disclosed |
| CN-101712828-A | Ink jet ink, ink jet recording method, and ink cartridge | CANON KK | 2010-05-26 | — | — | CN | disclosed |
| US-7674825-B2 | Dicarboxylic acid derivatives with pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2010-03-09 | — | — | US | disclosed |
| EP-0751767-A4 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE INC (US) | 1997-12-10 | — | — | EP | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| WO-1997015575-A1 | PROTEIN KINASE C MODULATORS. Y. | PROCYON PHARMACEUTICALS, INC. (US) | 1997-05-01 | — | — | WO | disclosed |
| EP-0751767-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1997-01-08 | — | — | EP | disclosed |
| EP-0645458-A1 | Chemoenzymatic process for production of S fenpropimorph | CAFFARO S.p.A. Società per l'Industria Chimica ed Elettrochimica (IT) | 1995-03-29 | — | — | EP | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |
| EP-0361040-A2 | Odorless multi-valent metal modified products of salicylic acid copolymers, production processes thereof, and use thereof as color-developing agents for pressure-sensitive copying paper sheets | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-04 | — | — | EP | disclosed |
| EP-0355544-A2 | Substituted decalin amines, method for their preparation and their use in pesticides | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |
| US-4277421-A | P-TERT-BUTYLBENZAL BROMIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-07 | — | — | US | disclosed |
| US-4261925-A | Surfactants | THE DOW CHEMICAL COMPANY (US) | 1981-04-14 | — | — | US | disclosed |