Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Docosanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decanol SCHEMBL29479873 | 1.00 | TSHR (0.59) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| Docosanol SCHEMBL30190460 | 1.00 | TSHR (0.59) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| 1-Hexanol SCHEMBL28823442 | 1.00 | TSHR (0.59) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| Cetyl Alcohol SCHEMBL29646603 | 1.00 | TSHR (0.59) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| Cetostearyl Alcohol SCHEMBL11667476 | 1.00 | TSHR (0.59) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| Decanol SCHEMBL22588989 | 1.00 | TSHR (0.59) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| Octanol SCHEMBL21708821 | 1.00 | TSHR (0.59) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| Cetyl Alcohol SCHEMBL22588991 | 1.00 | TSHR (0.59) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| Dodecanol SCHEMBL22588997 | 1.00 | TSHR (0.59) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| Acrylic Acid SCHEMBL30190526 | 1.00 | TSHR (0.59) | TSHRLMNAALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104010695-B | Personal care composition and method containing hydrophobically modified hydroxyethyl cellulose | 罗门哈斯公司 | 2017-09-15 | — | — | CN | claimed |
| EP-3249022-B1 | INKJET ADHESIVE, MANUFACTURING METHOD FOR SEMICONDUCTOR DEVICE, AND ELECTRONIC COMPONENT | SEKISUI CHEMICAL CO LTD (JP) | 2020-04-29 | — | — | EP | disclosed |
| US-10066118-B2 | Inkjet adhesive, manufacturing method for semiconductor device, and electronic component | SEKISUI CHEMICAL CO., LTD. (JP) | 2018-09-04 | — | — | US | disclosed |
| EP-3249022-A1 | INKJET ADHESIVE, MANUFACTURING METHOD FOR SEMICONDUCTOR DEVICE, AND ELECTRONIC COMPONENT | Sekisui Chemical Co., Ltd. (JP) | 2017-11-29 | — | — | EP | disclosed |
| CN-104010695-B | Personal care composition and method containing hydrophobically modified hydroxyethyl cellulose | 罗门哈斯公司 | 2017-09-15 | — | — | CN | disclosed |
| US-20170233599-A1 | INKJET ADHESIVE, MANUFACTURING METHOD FOR SEMICONDUCTOR DEVICE, AND ELECTRONIC COMPONENT | SEKISUI CHEMICAL CO., LTD. (JP) | 2017-08-17 | — | — | US | disclosed |
| CN-102604480-A | Robust curable solid inks | XEROX CORP | 2012-07-25 | — | — | CN | disclosed |