Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 20/20 | 0.66 |
| ▸ | KLKB1 | P03952 | 11/20 | 0.66 |
| ▸ | PLAT | P00750 | 4/20 | 0.66 |
| ▸ | KLK1 | P06870 | 1/20 | 0.66 |
| ▸ | F10 | P00742 | 3/20 | 0.54 |
| ▸ | PLG | P00747 | 2/20 | 0.50 |
| ▸ | F9 | P00740 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922777 | 0.89 | F11 (0.62) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1196973 | 0.88 | F11 (0.75) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1196978 | 0.88 | F11 (0.75) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1196975 | 0.88 | F11 (0.75) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1196976 | 0.88 | F11 (0.75) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1197058 | 0.86 | F11 (0.74) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1197056 | 0.86 | F11 (0.74) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1920316 | 0.83 | F11 (0.78) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1197118 | 0.83 | F11 (0.74) | F11KLKB1PLATKLK1F10 | |
| SCHEMBL1197119 | 0.83 | F11 (0.74) | F11KLKB1PLATKLK1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981854-B1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-06-01 | — | — | EP | claimed |