Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19207776 | 1.00 | RIPK1 (1.00) | RIPK1SCN9A | |
| SCHEMBL19207594 | 0.87 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207598 | 0.87 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207701 | 0.87 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL23337325 | 0.85 | RIPK1 (0.73) | RIPK1 | |
| SCHEMBL19224464 | 0.84 | RIPK1 (0.79) | RIPK1 | |
| SCHEMBL23349411 | 0.84 | RIPK1 (0.77) | RIPK1 | |
| SCHEMBL17312455 | 0.83 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL17312459 | 0.83 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL23337962 | 0.83 | RIPK1 (0.70) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414239-A2 | INHIBITORS OF RECEPTOR-INTERACTING PROTEIN KINASE 1 | Denali Therapeutics Inc. (US) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017136727-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. (US) | 2017-08-10 | — | — | WO | disclosed |