Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.48 |
| ▸ | MC5R | P33032 | 8/20 | 0.48 |
| ▸ | MC3R | P41968 | 7/20 | 0.48 |
| ▸ | MC1R | Q01726 | 7/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920759 | 0.83 | MC4R (0.45) | MC4RMC5RMC3RMC1RKCNH2 | |
| SCHEMBL1920256 | 0.82 | MC4R (0.48) | MC4RMC5RMC3RMC1RKCNH2 | |
| SCHEMBL1920459 | 0.80 | MC4R (0.45) | MC4RMC5RMC3RMC1RKCNH2 | |
| SCHEMBL1920391 | 0.78 | MC4R (0.64) | MC4RMC5RMC3RMC1RKCNH2 | |
| SCHEMBL70497 | 0.78 | MC4R (0.64) | MC4RMC5RMC3RMC1RKCNH2 | |
| SCHEMBL71984 | 0.78 | MC4R (0.64) | MC4RMC5RMC3RMC1RKCNH2 | |
| SCHEMBL3170759 | 0.78 | MC4R (0.64) | MC4RMC5RMC3RMC1RKCNH2 | |
| SCHEMBL15252713 | 0.78 | MC4R (0.64) | MC4RMC5RMC3RMC1RKCNH2 | |
| SCHEMBL91103 | 0.78 | MC4R (0.64) | MC4RMC5RMC3RMC1RKCNH2 | |
| SCHEMBL30593923 | 0.78 | MC4R (0.64) | MC4RMC5RMC3RMC1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716135-B1 | PIPERIDINYLCARBONYL-PYRROLIDINES AND THEIR USE AS MELANOCORTIN AGONISTS | PFIZER LTD (GB) | 2011-06-01 | — | — | EP | disclosed |