SCHEMBL1920958

SCHEMBL1920958

O=S(=O)(c1nc2ccccc2s1)N(C1CCCCC1)C1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PSMB8 P28062 1/20 0.53
▸ PSMB5 P28074 1/20 0.53
▸ CA12 O43570 1/20 0.51
▸ CA1 P00915 1/20 0.51
▸ CA2 P00918 1/20 0.51
▸ CA4 P22748 1/20 0.51
▸ CA7 P43166 1/20 0.51
▸ CA14 Q9ULX7 1/20 0.51
▸ CYP1A2 P05177 2/20 0.49
▸ CYP2D6 P10635 1/20 0.49
▸ MAOB P27338 1/20 0.47
▸ ALDH1A1 P00352 6/20 0.45
▸ KMT2A Q03164 5/20 0.45
▸ MEN1 O00255 4/20 0.45
▸ LMNA P02545 3/20 0.45
▸ MAPT P10636 2/20 0.45
▸ HTT P42858 2/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ CNR1 P21554 1/20 0.44
▸ SMN1; SMN2 Q16637 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29425017 1.00 PSMB8 (0.53) PSMB8PSMB5CA12CA1CA2
SCHEMBL11194115 0.86 PSMB8 (0.50) PSMB8PSMB5CA12CA1CA2
SCHEMBL28143745 0.84 PSMB8 (0.48) PSMB8PSMB5CA12CA1CA2
SCHEMBL11200209 0.84 ESR1 (0.51) PSMB8PSMB5CA12CA1CA2
SCHEMBL11196189 0.83 CYP1A2 (0.47) PSMB8PSMB5CA12CA1CA2
SCHEMBL11186831 0.82 TXN (0.47) PSMB8PSMB5CA12CA1CA2
SCHEMBL11201976 0.82 CYP1A2 (0.44) PSMB8PSMB5CA12CA1CA2
SCHEMBL11183918 0.81 CYP1A2 (0.46) PSMB8PSMB5CA12CA1CA2
SCHEMBL11188121 0.80 CYP1A2 (0.47) PSMB8PSMB5CA12CA1CA2
SCHEMBL11133585 0.80 CYP1A2 (0.45) PSMB8PSMB5CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4284636-A1 MULTILAYER RUBBER HOSE ContiTech USA, Inc. (US) 2023-12-06 — — EP claimed
CN-116806192-A Multi-layer rubber hose 康蒂泰克美国公司 2023-09-26 — — CN claimed
CN-115594887-B Preparation method of modified carbon nanotube and application of modified carbon nanotube in tire tread rubber 广东粤港澳大湾区黄埔材料研究院 2023-04-07 — — CN claimed
CN-115678118-A Rubber composition for high-wear-resistance tire, preparation method, vulcanized rubber and application 北京化工大学 2023-02-03 — — CN claimed
CN-115594887-A Preparation method of modified carbon nanotube and application of modified carbon nanotube in tire tread rubber 广东粤港澳大湾区黄埔材料研究院(CN) 2023-01-13 — — CN claimed
CN-115260694-A Rubber composition for run-flat tire sidewall support rubber and preparation method thereof 安徽佳通乘用子午线轮胎有限公司 2022-11-01 — — CN claimed
CN-111533883-B Ship filling sealing damping vibration attenuation material and preparation method thereof 青岛爱尔家佳新材料股份有限公司 2022-10-28 — — CN claimed
CN-111981125-B High-strength high-resilience low-temperature-resistant sealing ring and preparation method thereof 莱州市金城橡胶制品有限责任公司 2022-07-29 — — CN claimed
CN-114437430-A High-wear-resistance rubber-based composite material and preparation method thereof 青岛科技大学 2022-05-06 — — CN claimed
CN-114316383-A Heat-conducting high-damping vibration-damping rubber material and preparation method and application thereof 东风商用车有限公司 2022-04-12 — — CN claimed
EP-1958983-B1 Silica reinforced rubber composition and use in tires GOODYEAR TIRE & RUBBER (US) 2012-08-29 — — EP claimed
EP-2072282-A1 Tire containing an internal cord reinforced rubber component THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-06-24 — — EP claimed
EP-1635822-A4 METHODS AND COMPOSITIONS FOR TREATING RHEUMATOID ARTHRITIS ELAN PHARM INC (US) 2009-06-24 — — EP claimed
US-20090151838-A1 TIRE CONTAINING AN INTERNAL CORD REINFORCED RUBBER COMPONENT SANDSTROM ERIK PAUL 2009-06-18 — — US claimed
JP-2007526230-A — — 2007-09-13 — — JP claimed
EP-1635822-A2 METHODS AND COMPOSITIONS FOR TREATING RHEUMATOID ARTHRITIS Elan Pharmaceuticals, Inc. (US) 2006-03-22 — — EP claimed
WO-2005000246-A2 METHODS AND COMPOSITIONS FOR TREATING RHEUMATOID ARTHRITIS ELAN PHARMACEUTICALS, INC. (US) 2005-01-06 — — WO claimed
CN-1536031-A Polycrystalline state composite and its preparation method 陈书怡 2004-10-13 — — CN claimed
US-6635327-B2 Utilized as a vibration damping, sound absorptive, impact absorptive, vibration-proof, electromagnetic wave absorptive, piezoelectric, and endothermal material as well as a polarity liquid SHISHIAI-KABUSHIKIGAISHA (JP) 2003-10-21 — — US claimed
US-20020031626-A1 Method of energy conversion OHIRA YASUYUKI (JP) 2002-03-14 — — US claimed
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