Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11496972 | 0.83 | CHRM1 (0.43) | ACE2MMEACECPA1FAAH | |
| SCHEMBL25342792 | 0.82 | MME (0.41) | ACE2MMEACECPA1CYP2D6 | |
| SCHEMBL21441515 | 0.80 | MME (0.40) | ACE2MMEACECPA1CYP2D6 | |
| SCHEMBL24059966 | 0.80 | MME (0.40) | ACE2MMEACECPA1CYP2D6 | |
| Hydrochloric Acid SCHEMBL30731552 | 0.80 | MME (0.40) | ACE2MMEACECPA1CYP2D6 | |
| Hydrochloric Acid SCHEMBL28550969 | 0.80 | MME (0.40) | ACE2MMEACECPA1CYP2D6 | |
| SCHEMBL15694717 | 0.78 | ACE2 (0.39) | ACE2MMEACECPA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7262796 | 0.78 | MME (0.39) | ACE2MMEACECPA1CYP2D6 | |
| SCHEMBL574633 | 0.78 | CYP2D6 (0.50) | ACE2MMEACECPA1CYP2D6 | |
| SCHEMBL10954429 | 0.78 | CYP2D6 (0.50) | ACE2MMEACECPA1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709288-A | Phosphamide derivative and preparation method and application thereof | 四川海思科制药有限公司 | 2018-02-16 | — | — | CN | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |