Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209714 | 0.83 | ACE2 (0.41) | ACE2FAAHMMEACECPA1 | |
| SCHEMBL10954429 | 0.75 | CYP2D6 (0.50) | TSHRACE2MMEACECPA1 | |
| SCHEMBL574633 | 0.75 | CYP2D6 (0.50) | TSHRACE2MMEACECPA1 | |
| SCHEMBL6722464 | 0.74 | CYP2D6 (0.56) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL25342792 | 0.74 | MME (0.41) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL6034543 | 0.73 | TSHR (0.52) | TDP1TSHRACE2FAAHLCK | |
| SCHEMBL6034547 | 0.73 | TSHR (0.52) | TDP1TSHRACE2FAAHLCK | |
| SCHEMBL28817970 | 0.73 | LCK (0.52) | ACE2FAAHLCKPPARDZDHHC20 | |
| SCHEMBL4582873 | 0.73 | TP53 (0.41) | ACE2FAAHMMEACECPA1 | |
| SCHEMBL2559274 | 0.73 | TP53 (0.41) | ACE2FAAHMMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4280008-A | CHEMICAL INTERMEDIATES FOR OPTICALLY ACTIVE AMINO ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |