SCHEMBL19209752

SCHEMBL19209752

COCCOC(=O)[C@H](C)NC(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA12 O43570 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CYP2D6 P10635 1/20 0.42
KMT2A Q03164 1/20 0.41
CTSK P43235 8/20 0.40
CTSS P25774 4/20 0.40
KDM4E B2RXH2 1/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
GLS O94925 1/20 0.40
CTSL P07711 1/20 0.38
CTSB P07858 1/20 0.38
EPHX2 P34913 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19209751 1.00 CA1 (0.46) CA1CA2CA7CA12CA14
SCHEMBL28038739 0.95 CA1 (0.43) CA1CA2CA7CA12CA14
SCHEMBL28038740 0.95 CA1 (0.43) CA1CA2CA7CA12CA14
SCHEMBL16390624 0.95 CA1 (0.43) CA1CA2CA7CA12CA14
SCHEMBL23818884 0.85 CA1 (0.47) CA1CA2CA7CA12CA14
SCHEMBL22964295 0.85 CA1 (0.47) CA1CA2CA7CA12CA14
SCHEMBL28065097 0.85 CA1 (0.47) CA1CA2CA7CA12CA14
SCHEMBL11602026 0.85 CA1 (0.47) CA1CA2CA7CA12CA14
SCHEMBL28065095 0.85 CA1 (0.47) CA1CA2CA7CA12CA14
SCHEMBL24097644 0.84 CTSK (0.51) CA1CA2CA7CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed
CN-107709288-A Phosphamide derivative and preparation method and application thereof 四川海思科制药有限公司 2018-02-16 CN disclosed
WO-2017133517-A1 PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF 四川海思科制药有限公司 2017-08-10 WO disclosed
WO-2017133517-A1 PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF 四川海思科制药有限公司 2017-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A CA1 4717/4885CA2 2768/4885CA7 3777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.