Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 18/20 | 0.57 |
| ▸ | CDK4 | P11802 | 9/20 | 0.57 |
| ▸ | CCND1 | P24385 | 5/20 | 0.57 |
| ▸ | CCND3 | P30281 | 10/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.56 |
| ▸ | CDK2 | P24941 | 2/20 | 0.56 |
| ▸ | CDK1 | P06493 | 6/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.55 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209876 | 0.94 | CDK6 (0.65) | CDK6CDK4CCND1CCND3CCNE2 | |
| SCHEMBL19209833 | 0.92 | CDK6 (0.54) | CDK6CDK4CCND1CCND3CCNE2 | |
| SCHEMBL19231855 | 0.91 | CDK6 (0.54) | CDK6CDK4CCND1CCND3CCNE2 | |
| SCHEMBL19209828 | 0.90 | CDK6 (0.52) | CDK6CDK4CCND1CCND3CDK2 | |
| SCHEMBL19231819 | 0.88 | CDK6 (0.51) | CDK6CDK4CCND1CCND3CDK1 | |
| SCHEMBL19231814 | 0.88 | CDK6 (0.51) | CDK6CDK4CCND1CCND3CDK1 | |
| SCHEMBL19209858 | 0.87 | CDK6 (0.73) | CDK6CDK4CCND1CCND3CCNE2 | |
| SCHEMBL19231817 | 0.87 | CDK6 (0.51) | CDK6CDK4CCND1CCND3CDK1 | |
| SCHEMBL19231821 | 0.87 | CDK6 (0.51) | CDK6CDK4CCND1CCND3CDK1 | |
| SCHEMBL19209824 | 0.87 | CDK6 (0.51) | CDK6CDK4CCND1CCND3CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133701-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2017-08-10 | — | — | WO | claimed |
| CN-108602799-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2021-08-03 | — | — | CN | disclosed |
| WO-2017133701-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2017-08-10 | — | — | WO | disclosed |