Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 18/20 | 0.57 |
| ▸ | CCND1 | P24385 | 11/20 | 0.57 |
| ▸ | CDK4 | P11802 | 3/20 | 0.52 |
| ▸ | CCND3 | P30281 | 3/20 | 0.52 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.52 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | PIM1 | P11309 | 2/20 | 0.52 |
| ▸ | CIT | O14578 | 1/20 | 0.52 |
| ▸ | GAK | O14976 | 1/20 | 0.52 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.52 |
| ▸ | STK16 | O75716 | 1/20 | 0.52 |
| ▸ | CCNK | O75909 | 1/20 | 0.52 |
| ▸ | STK10 | O94804 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19231833 | 0.92 | CDK6 (0.54) | CDK6CCND1CDK4DYRK2CDK2 | |
| SCHEMBL19209837 | 0.91 | CDK6 (0.69) | CDK6CCND1CDK4CCND3DYRK2 | |
| SCHEMBL17488688 | 0.90 | CDK4 (0.65) | CDK6CCND1CDK4CCND3DYRK2 | |
| SCHEMBL19231836 | 0.90 | CDK6 (0.53) | CDK6CCND1CDK4DYRK2PIM1 | |
| SCHEMBL19231730 | 0.90 | CDK6 (0.53) | CDK6CCND1CDK4CCND3DYRK2 | |
| SCHEMBL19231735 | 0.89 | CDK6 (0.53) | CDK6CCND1CDK4CCND3DYRK2 | |
| SCHEMBL19231733 | 0.88 | CDK6 (0.62) | CDK6CCND1CDK4CCND3DYRK2 | |
| SCHEMBL19209847 | 0.86 | CDK6 (0.68) | CDK6CCND1CDK4CCND3DYRK2 | |
| SCHEMBL19209887 | 0.86 | CDK6 (0.55) | CDK6CCND1CDK4CCND3DYRK2 | |
| SCHEMBL19231737 | 0.85 | CDK6 (0.64) | CDK6CCND1DYRK2CDK2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133701-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2017-08-10 | — | — | WO | claimed |
| CN-108602799-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2021-08-03 | — | — | CN | disclosed |
| WO-2017133701-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2017-08-10 | — | — | WO | disclosed |