Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.48 |
| ▸ | PRCP | P42785 | 3/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620066 | 0.91 | PRCP (0.55) | HTR2CPRCPTERTHTR2BKDM4E | |
| SCHEMBL620067 | 0.91 | PRCP (0.55) | HTR2CPRCPTERTHTR2BKDM4E | |
| SCHEMBL8789170 | 0.91 | PRCP (0.55) | HTR2CPRCPTERTHTR2BKDM4E | |
| Trifluoroacetic Acid SCHEMBL5231460 | 0.87 | HTR2C (0.48) | HTR2CPRCPTERTHTR2BKDM4E | |
| Trifluoroacetic Acid SCHEMBL3332141 | 0.86 | PRCP (0.56) | HTR2CPRCPHTR2BKDM4ECTSC | |
| SCHEMBL6372058 | 0.85 | PRCP (0.50) | HTR2CPRCPTERTHTR2BKDM4E | |
| SCHEMBL10788824 | 0.84 | TERT (0.51) | HTR2CPRCPTERTHTR2BKDM4E | |
| Glycine SCHEMBL2933526 | 0.84 | PRCP (0.50) | HTR2CPRCPTERTHTR2BKDM4E | |
| SCHEMBL10788841 | 0.84 | TERT (0.51) | HTR2CPRCPTERTHTR2BKDM4E | |
| SCHEMBL31142126 | 0.84 | TERT (0.51) | HTR2CPRCPTERTHTR2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133701-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2017-08-10 | — | — | WO | disclosed |